
Review by Eleanor J. Bader
In January 2020, right before the COVID-19 pandemic shutdowns went into effect, Dr. Melody Glenn took a part-time job at a methadone clinic in Tucson, Arizona. What she found was both appalling and frustrating. First, there was the staff’s condescension toward patients, all of whom were forced to wait in line to get a single dose of a drug that was meant to keep them from using heroin or other opioids. Then there were the periodic tox screenings and the mandatory supervision of patients who resented the constant oversight. Add in the public’s frequently-expressed apprehension about allowing a clinic for people who use drugs to exist in their communities, and it’s easy to see how and why staff burn out and become discouraged.
And it is not just methadone: According to Glenn, a similar reaction surrounds buprenorphine, a less-stringently regulated drug that also helps people reduce opioid dependency. As she began to probe the scorn surrounding these drugs, Glenn learned of Dr. Marie Nyswander, a once-prominent, if always controversial, New York physician who is credited with creating methadone. The unfolding story chronicles Nyswander’s complicated life – she was overtly critical of feminism despite being a pioneer in a largely male world – and reveals the many factors that have made – and continue to make – providing compassionate care to drug users difficult to sustain.
Glenn is a forceful advocate of harm reduction, and Mother of Methadone advocates a range of ways that the medical and social justice worlds can work together to create safe injection sites, distribute clean syringes and fentanyl test strips, and promote the use of Naloxone to reverse overdoses and prevent needless death. What’s more, the book offers a sensitive and progressive vision of medical care and presents a cogent argument against the continued criminalization of drug use.
Mother of Methadone: A Doctor’s Quest, A Forgotten History, and a Modern-Day Crisis by Melody Glenn. Beacon Press, July 2025.
Reviewer bio: Eleanor J. Bader is a Brooklyn, NY-based journalist who writes about books and domestic social issues for Truthout, Rain Taxi, The Progressive, Ms. Magazine, the Los Angeles Review of Books, and The Indypendent.